Cleveland Clinic’s New Neurological Institute Building Nears 2027 Opening, Expanding Inpatient, Surgery, Imaging and Research

A one-million-square-foot neurology hub planned for Cleveland Clinic’s main campus

Cleveland Clinic is building a dedicated Neurological Institute facility on its main campus that is expected to begin receiving patients in early 2027. The project is designed to consolidate major components of neurological care—outpatient visits, inpatient hospitalization, surgical services, imaging and rehabilitation—into a single building while adding embedded technology intended to support diagnostics and research.

The facility is planned as a 1-million-square-foot addition to Cleveland Clinic’s main campus footprint, and Cleveland Clinic has described it as the largest building on the campus. The building’s development has included milestone construction events through 2025, as the exterior structure and enclosure progressed toward interior buildout and systems installation.

What the building is expected to include

Program details released by Cleveland Clinic outline a mix of inpatient and outpatient capacity, along with surgical suites and advanced imaging. The planned configuration includes:

• 210 inpatient rooms designed to support mobility and neurological recovery needs
• 120 outpatient exam rooms equipped with interactive technologies
• 36 neurological intensive care unit beds
• 14 operating rooms at opening, with surgical and interventional capabilities for neurological conditions
• Multiple MRI areas (Cleveland Clinic has cited six MRI areas in its building-by-the-numbers summary)

Cleveland Clinic has also described a skybridge connection to the main hospital complex, an element intended to integrate patient movement and clinical operations across adjacent inpatient services on campus.

Rehabilitation and “assessment center” technology embedded into patient flow

A notable design focus is the integration of data collection into routine patient movement and check-in. Cleveland Clinic has outlined plans for an automated assessment center that patients encounter during arrival and registration, aimed at capturing objective measures related to neurological performance. Separately described features include a gait and mobility assessment center and a large rehabilitation gym intended for therapy and recovery services.

Cleveland Clinic has framed the building as a “smart” clinical environment in which consent-based tools and sensors can help document neuroperformance measures such as gait and mobility in real-world clinical settings.

The health system has also said it plans virtual technology in inpatient rooms to support continuous monitoring, linking hospital care to a broader strategy that includes digital services and distance health consultations across Cleveland Clinic sites in the U.S. and internationally.

Research integration and flexible clinical space

The new facility is planned to combine clinical operations with research space intended to support studies of brain function and the development of new therapies. Cleveland Clinic has described flexible, modular layouts to allow rooms and care areas to be modified as clinical needs, staffing models and technologies evolve.

If the early-2027 timeline holds, the building will open at a point when demand for neurological services is expected to remain high across aging populations, while health systems increasingly emphasize coordinated specialty care and technology-enabled monitoring. Cleveland Clinic’s design choices suggest the building is intended not only as added capacity, but also as an operational model linking inpatient care, outpatient evaluation, rehabilitation, imaging and research under one roof.